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  • Activity of the human centrosomal kinase, nek2, depends on an unusual.
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  • Localization studies have shown that nek2 is a core component of the centrosome, the microtubule organizing center of the cell, and functional approaches suggest.
  • Nek2a kinase stimulates centrosome disjunction and is.
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  • Nek2 is a human cell cycleregulated kinase that is structurally related to the mitotic regulator, nima, of aspergillus nidulans.
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Cell cycle kinases represent an important component of the cell machinery that controls signal transduction involved in cell proliferation, growth, and differentiation.

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